Endocrine Abstracts

Objective: To determine the peculiarity of melatonin (M) at women with polycystic ovary syndrome (PCOS).Methods: Fifty-six women with PCOS from 18 to 29 years old have been included in research. Control group 22 healthy women with regular menses, same age. Levels M were determined in the blood at 2 and 8 o’clock in the morning on a fifth day menstrual cycle in January and July.Results: It is established, that the level of M in...

Background and aims: The long-acting somatostatin analogs represent are nowadays the first-line medical treatment of acromegaly. To assess the efficacy and tolerability of lanreotide-SR (LSR) in the treatment of active acromegaly.Subjects and methods: Eleven patients (2 men and 9 women; aged 27–75 years, median 47.4 years) were treated in whom active acromegaly with during disease from 1 to 34 years. All patients had the macroadenoma of hypophysis i...

Type 2 diabetes mellitus (T2DM) is an insulin-resistant state characterized by an increased low-level inflammation and oxidative stress which are probably the initiation of diabetes-related cardiovascular complications. The aim of the study was to evaluate the impact of Mediterranean-style diet on inflammation and atherosclerosis markers in T2DM patients. Twenty-five overweight/obese T2DM patients (age 54.1±1.9 years, diabetes duration 7.8±1.3 years, HbA1c...